An introduction to state of the art experimental design approaches used to understand and interpret repeated measurements and cross over designs featuring a host of essential concepts for research and experimentation repeated measurements and cross over designs explores a variety of disciplines that can benefit from the presented methods and results to achieve optimal experimental designs. Repeated measurements and cross over designs features the close tie between the design analysis and presentation of results presents principles and rules that apply very generally to most areas of research such as clinical trials agricultural investigations industrial procedures quality control procedures and epidemiological studies. Repeated measurements and cross over designs october 2016 journal of quality technology 484416 417 doi 101080 00224065201611918178 authors rachel t silvestrini request full text pdf . You can think of the repeated measures design in this simplified example as representing what happens in the first period of the cross over design however while the repeated measures design ends after the first week the cross over design continues for a second week with subjects switching treatments. Repeated measurements and cross over designs wiley an introduction to state of the art experimental design approaches to better understand and interpret repeated measurement data in cross over designs